More Posts About: Liver Disease

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Patients with hepatic iron overload who undergo orthotopic liver transplantation (OLT) have a worse 1-year survival than those who undergo transplantation for other indications; the long-term outcome in this population is unknown. The purpose of this study is to report long-term follow-up after OLT in a cohort of patients with hepatic iron overload. [...]
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Diabetes mellitus is a disorder of glucose metabolism that affects 12 million people in the United States. 48 Diabetes primarily affects the liver and biliary system through its metabolic effects. Patients with either type I or type II diabetes of sufficient duration, including patients with secondary etiologies of diabetes such as chronic pancreatitis [...]
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Diabetic gastroparesis is a common, underrecognized disorder affecting both type I and type II diabetics usually in the setting of other diabetic complications. The pathogenesis of diabetic gastroparesis is poorly understood, but autonomic neuropathy appears to play a major role. The symptoms of gastroparesis are nonspecific, and complications such [...]
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Cirrhotic patients with hereditary hemochromatosis (HHC) have an increased risk of primary liver cancer (PLC). The purpose of this study was to determine the prevalence of primary liver cancer in patients with HHC undergoing orthotopic liver transplantation (OLT). Five liver transplant centers were surveyed; clinical and pathological data on 37 patients [...]
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Two patients with liver failure secondary to isoniazid hepatotoxicity were successfully treated with orthotopic liver transplantation. A 49-year-old man received isoniazid prophylaxis for a positive tuberculin test, and a 60-year-old woman was treated for active pulmonary tuberculosis with isoniazid, rifampin, and pyrazinamide. Both patients developed [...]
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Hereditary hemochromatosis (HH) is a genetic disorder of iron metabolism. It is an uncommon indication for liver transplantation (LT). It has been suggested that patients who undergo LT for cirrhosis related to HH have higher morbidity and mortality from cardiac, infectious and malignant complications. The purpose of this retrospective review was to [...]